We have 3 dogs in the house—two large and one small. We buy this primarily for my 28 pound female beagle, Beatrix; but it’s nice to have it on hand for the larger dogs for pain; we just does down for her. Bea is responding well to it—she has a disc disease and her pain is lessened with this. We also used it for Madigan, our boxer mastiff, when she was spayed, and it helped—she was a rescue from the pound and they didn’t provide any pain meds. Her mood changed quickly when she was given this.
We didn’t see much improvement for anxiety for our 80 pound treeing walker coonhound; however, we were just experimenting with that.